
Department of Public Health
As the public health agency for the State of South Carolina, the South Carolina Department of Public Health’s (DPH) mission is to protect, promote, and improve the health and well-being of everyone in South Carolina. With more than 2,900 employees working in approximately 90 locations across the state, DPH instills a people-first approach to all that we do. This includes working with our partners, communities, and others to help every South Carolinian have the access, resources, and information they need to make decisions that enhance their health and have access to the highest quality, safe health care.
- Family and Social Agencies
- General Services Agencies

Department of Public Safety
The South Carolina Department of Public Safety (SCDPS) enforces laws governing traffic, motor vehicles and commercial carriers.
- Public Safety Agencies

Department of Revenue
The South Carolina Department of Revenue's (SCDOR) mission is to administer the revenue and regulatory laws of the state with integrity, effectiveness and fairness to all taxpayers, while maintaining the highest security and the protection of taxpayer information.
- Business Agencies
- Economic Agencies
- Employment Agencies
- General Services Agencies
- Licensing Agencies
- Taxes and Finance Agencies

Department of Social Services
The South Carolina Department of Social Services (SCDSS) provides assistance and protection programs for the state's citizens.
- Family and Social Agencies

Department of Transportation
The South Carolina Department of Transportation (SCDOT) is the complete resource for the state's transportation system.
- Transportation Agencies